Rashford has enjoyed a prolific season for the Red Devils, scoring 29 goals in all competitions.
Ten Hag also confirmed that Rafael Varane is fully fit after missing in action for a month.
“Rapha Varane is back and Rashford is doubtful,” Ten Hag told reporters.
“He has a problem, so (it is an) injury on his leg. He’s a big question mark for tomorrow but happy Rapha Varane is back.
“We have players who can score goals and they have the opportunity now to show it. Varane is experienced, knows how to win and will lead how to win, will guide us.
“Alejandro Garnacho has one more week training, definitely, so he is available. We have seen he can bring something extra in the team.”
Manchester United have lost their last two Premier League matches against Brighton and West Ham to question their top four hopes.
“We know that (Liverpool’s run) but it’s not important because we have everything in our hands… As long as we have everything in our hands then we are not dependent on them,” the Dutch manager said.
“What is important is the opponent we face tomorrow: Wolves. We have to take them seriously. They have done a great job… but they also have deficits, (we must) take advantage of that.
“We are convinced with what we are doing, we have a lot of success, we have won a lot of games.”
Liverpool have won their last six Premier League matches to make a late push for Champions League qualification.