Christophe Galtier confirmed on Friday that the former Barcelona captain will return to the starting eleven on Saturday.
“I spoke with him on Tuesday to see what his mindset was and I found him very determined to play… He will start tomorrow,” Galtier told a press conference.
Messi was back in training on Monday after being suspended for making an unauthorised trip to Saudi Arabia and missing a training session as a result.
French media reported that Messi was suspended for two weeks after making the trip when he was supposed to train with the squad the day after the Ligue 1 leaders’ 3-1 defeat to Lorient last month.
Messi apologised to PSG and his team mates last Friday and was left out of the squad for their 3-1 win at second-bottom Troyes two days later.
PSG are six points clear of Lens and eight in front of third-placed Olympique de Marseille with four games remaining this season.